There is probably more history connected with Gainesville than any other village in Greene County.

In 1846 Gainesville consisted of a log court house , two store buildings an five dwellings houses. The community did not have a name until it "gained" the location of the county seat in 1840 , an hence became "Gainesville". At its height , the town had a population of about three hundred or three fifty in 1884.

The first newspaper in Greene County was established in 1874 by Rev. J. D. C. Cobb, Frank M. Daulton published a paper at Gainesville for a number of years.

When the county seat was moved to Paragould late in 1884 , the business and professional men moved to Paragould , leaving their homes to go down in disuse. The majority of the population followed. Since then the community has consisted almost entirely of farmers.

Notes found in "The History of Greene County" author Vivian Hansbrough.